peritrabecular

— Histogram intersection is calculated for direct and indirect interaction (RBF direct and RBF indirect ). a Nodular, peritrabecular infiltration (intersection 0.81 ± 0.05 for direct and 0.88 ± 0.03 for indirect interaction). b Nodular, non-peritrabecular infiltration (intersection 0.51 ± 0.05 for direct and 0.77 ± 0.02 for indirect interaction). c Diffuse bone marrow infiltration (intersection 0.66 ± 0.013 for direct and 0.82 ± 0.05 for indirect interaction) The herein presented approach (compare Additional file 1 : Figure S1) enables to run morphological analysis of bone marrow infiltrates, which is a demanding task due to – amongst other – highly complex immunophenotypes (e.g.