pegRNA

名词 n.

英文释义

名词 n.
  1. A specialized guide RNA used in prime editing, comprising a single guide RNA (sgRNA) extended with a primer binding site (PBS) and a reverse transcription template (RTT) that encodes the desired genetic edit. countable,uncountable
    — Prime editors (PEs), initially represented by PE1, employed a reverse transcriptase (RT) fused to an RNA-programmable nickase (Cas9n) and a prime editing guide RNA (pegRNA) to directly copy genetic information from the extension on the pegRNA into the target genomic locus.

词形变化

pegRNAs plural

词源

Acronym of prime editing guide RNA.
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