decernotinib
名词 n.
英文释义
名词 n.
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An experimental medication belonging to the class of Janus kinase inhibitors.
— Developed to target the kinase domain of JAK3, decernotinib (VX-509) showed selective in vitro inhibition of JAK3 over the other JAKs and efficacy in RA (73, 74). However, a CYP3A4-mediated drug–drug interaction was also described, potentially limiting the use of decernotinib; development of this molecule has currently been halted (75).
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