chromothripsis

名词 n.
中文释义

英文释义

名词 n.
  1. A multiple of chromosomal rearrangements that is associated with some cancers. uncountable
    — But for 2—3% of cancers, particularly bone cancer (up to 25%), recent evidence suggests that a single event of chromothripsis involving one or a few chromosomes leads to multiple gene rearrangements (in some cases tens to hundreds) that can disrupt tumor suppressor genes and/or produce oncogenic fusion genes.

词源

From Ancient Greek χρῶμα (khrôma, “colour”) (referring to English chromo(some)) + θρίψις (thrípsis, “shattering into pieces”) (from τρίβω (tríbō, “I rub”).
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