anfibatide

名词 n.

英文释义

名词 n.
  1. An antithrombotic agent binding to the GPIbα subunit of the glycoprotein Ib-IX-V complex, purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). uncountable
    — Anfibatide is an anticoagulant C-type lectin-like protein purified from the venom of the sharp-nosed viper (Deinagkistrodon acutus). […] The anticoagulant activity of anfibatide is due to its strong binding to human platelet glycoprotein Ib α-chain (GPIbα), which inhibits the binding of GPIbα with von Willebrand factor (VWF) and thrombin^(124,125) (Fig. 6a).
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